| 1 | 
									[ adverb ] usually; as a rule  Synonyms Examples "by and large it doesn't rain much here" Used in print(E. Gellhorn, "Prolegomena to a theory of the emotions"...) It seems to follow that by_and_large an antagonism exists between the paleo - and the neocortex as_far_as emotional reactivity is concerned , and that the balance between the two systems determines the emotional responsiveness of the organism . | 
| * |  |