[ noun ] (medicine,pathology) development of excess fibrous connective tissue in an organ
Used in print(J. W. C. Hagstrom et al., "Debilitating muscular...)
Splenomegaly was first noted in 1956 , and a sternal marrow biopsy at that time showed `` scattered foci of fibrosis '' suggestive_of myelofibrosis .
Microscopically , there was emphysema , fibrosis , and vascular congestion .
There were slight fibrosis and marked arteriolosclerosis .
Microscopically , both kidneys showed many small cortical scars in which there was glomerular and interstitial fibrosis , tubular atrophy , and an infiltration of lymphocytes and plasma cells .
There was no evidence of fibrosis .